Western 2021 Fixture
| Week | RD | Date | Time | Venue | Home Team | Away Team |
| 1 | 1 | Friday March 19 | 7.50 pm | MCG | Nth-East Magpies | Western Bulldogs |
| 2 | 2 | Sunday March 28 | 7.25 pm | Docklands | Western | West |
| 3 | 3 | Friday April 2 | 4.20 pm | Docklands | Northern Kangaroos | Western Bulldogs |
| 4 | 4 | Saturday April 10 | 2.45 pm | Mars | Western Bulldogs | Brisbane Lions |
| 5 | 5 | Saturday April 17 | 2.45 pm | Docklands | Western | Gold |
| 6 | 6 | Friday April 23 | 8.20 pm | Canberra | Western | Western |
| 7 | 7 | Saturday May 1? | 1.00 pm? | MCG | Eastern Tigers | Western Bulldogs |
| 8 | 8 | Saturday May 8? | 1.00 pm? | Docklands | Western Bulldogs | Northern Blues |
| 9 | 9 | Sunday May 15? | 1.00 pm? | Adelaide Oval | Port | Western |
| 10 | 10 | Saturday May 22? | 1.00 pm? | Docklands | Western Bulldogs | Southern Saints |
| 11 | 11 | Saturday May 29? | 1.00 pm? | Docklands | Western Bulldogs | Central Demons |
| 12 | 12 | Saturday June 5? | 1.00 pm? | Perth | Fremantle Dockers | Western Bulldogs |
| 13 | 13 | Saturday June 12 | Bye | |||
| 14 | 14 | Saturday June 19? | 1.00 pm? | Kardinia Park | Country Cats | Western Bulldogs |
| 15 | 15 | Saturday June 26? | 3.00 pm? | Perth Stadium | West | Western |
| 16 | 16 | Saturday July 3? | 1.00 pm? | Docklands | Western Bulldogs | Northern Kangaroos |
| 17 | 17 | Saturday July 10? | 1.00 pm? | Docklands | Western Bulldogs | Sydney Swans |
| 18 | 18 | Saturday July 17? | 1.00 pm? | Docklands | Gold | Western Bulldogs |
| 19 | 19 | Saturday July 24? | 1.00 pm? | Mars | Western Bulldogs | Adelaide Crows |
| 20 | 20 | Saturday July 31? | 1.00 pm? | MCG | Central Demons | Western Bulldogs |
| 21 | 21 | Saturday August 7? | 1.00 pm? | Docklands | Western Bulldogs | Nth-Western Bombers |
| 22 | 22 | Saturday August 14? | 1.00 pm? | Launceston | Eastern Hawks | Western Bulldogs |
| 23 | 23 | Saturday August 21? | 1.00 pm? | Docklands | Western | Port Bay |
| 24 | Bye Round or The End | Saturday August 28 | 1.00 pm? | |||
| 25 | Finals 1 | Saturday September 3? | 1.00 pm? | 2021 | Finals | Series |
| 26 | Finals 2 | Saturday Sept 10? | 1.00 pm? | 2021 | Finals | Series |
| 27 | Preliminary Final | Saturday Sept 17? | 1.00 pm? | 2021 | Finals | Series |
| 28 | Grand Final | Saturday Sep 24 | 1.00 pm? | 2021 | Finals | Series |
Ladder
| Team | P | W | L | D | PF | PA | % | Pts |
| Central Demons | 10 | 10 | - | - | 938 | 580 | 161.72 | 40 |
| Brisbane Lions | 10 | 8 | 2 | - | 1065 | 745 | 142.95 | 32 |
| Northern Blues | 10 | 8 | 2 | - | 932 | 813 | 114.64 | 32 |
| Fremantle Dockers | 10 | 7 | 3 | - | 780 | 608 | 128.29 | 28 |
| Southern Saints | 10 | 7 | 3 | - | 850 | 720 | 118.06 | 28 |
| Country Cats | 10 | 6 | 4 | - | 916 | 734 | 124.80 | 24 |
| Sydney Swans | 10 | 6 | 4 | - | 937 | 778 | 120.44 | 24 |
| Eastern Tigers | 10 | 6 | 4 | - | 979 | 813 | 120.42 | 24 |
| Western Bulldogs | 10 | 5 | 5 | - | 871 | 787 | 110.67 | 20 |
| Northern Magpies | 10 | 5 | 5 | - | 883 | 860 | 102.67 | 20 |
| Port Power | 10 | 4 | 5 | - | 752 | 730 | 103.01 | 16 |
| Coast Gold | 10 | 4 | 6 | - | 787 | 841 | 93.58 | 16 |
| Eastern Hawks | 10 | 3 | 6 | - | 877 | 947 | 92.61 | 16 |
| Greater Western | 10 | 3 | 6 | - | 776 | 896 | 85.61 | 12 |
| Adelaide Crows | 10 | 2 | 7 | - | 756 | 943 | 80.17 | 8 |
| Western Bombers | 10 | 2 | 8 | - | 735 | 1002 | 73.35 | 8 |
| Northern Kangaroos | 10 | 1 | 9 | - | 574 | 1070 | 53.64 | 4 |
| Coast West | 10 | 1 | 9 | - | 574 | 1115 | 51.48 | 4 |
