Western 2021 Fixture
| Week | RD | Date | Time | Venue | Home Team | Away Team |
| 1 | 1 | Friday March 19 | 7.50 pm | MCG | Nth-East Magpies | Western Bulldogs |
| 2 | 2 | Sunday March 28 | 7.25 pm | Docklands | Western | West |
| 3 | 3 | Friday April 2 | 4.20 pm | Docklands | Northern Kangaroos | Western Bulldogs |
| 4 | 4 | Saturday April 10 | 2.45 pm | Mars | Western Bulldogs | Brisbane Lions |
| 5 | 5 | Saturday April 17 | 2.45 pm | Docklands | Western | Gold |
| 6 | 6 | Friday April 23 | 8.20 pm | Canberra | Western | Western |
| 7 | 7 | Saturday May 1? | 1.00 pm? | MCG | Eastern Tigers | Western Bulldogs |
| 8 | 8 | Saturday May 8? | 1.00 pm? | Docklands | Western Bulldogs | Northern Blues |
| 9 | 9 | Sunday May 15? | 1.00 pm? | Adelaide Oval | Port | Western |
| 10 | 10 | Saturday May 22? | 1.00 pm? | Docklands | Western Bulldogs | Southern Saints |
| 11 | 11 | Saturday May 29? | 1.00 pm? | Docklands | Western Bulldogs | Central Demons |
| 12 | 12 | Saturday June 5? | 1.00 pm? | Perth | Fremantle Dockers | Western Bulldogs |
| 13 | 13 | Saturday June 12 | Bye | |||
| 14 | 14 | Saturday June 19? | 1.00 pm? | Kardinia Park | Country Cats | Western Bulldogs |
| 15 | 15 | Saturday June 26? | 3.00 pm? | Perth Stadium | West | Western |
| 16 | 16 | Saturday July 3? | 1.00 pm? | Docklands | Western Bulldogs | Northern Kangaroos |
| 17 | 17 | Saturday July 10? | 1.00 pm? | Docklands | Western Bulldogs | Sydney Swans |
| 18 | 18 | Saturday July 17? | 1.00 pm? | Docklands | Gold | Western Bulldogs |
| 19 | 19 | Saturday July 24? | 1.00 pm? | Mars | Western Bulldogs | Adelaide Crows |
| 20 | 20 | Saturday July 31? | 1.00 pm? | MCG | Central Demons | Western Bulldogs |
| 21 | 21 | Saturday August 7? | 1.00 pm? | Docklands | Western Bulldogs | Nth-Western Bombers |
| 22 | 22 | Saturday August 14? | 1.00 pm? | Launceston | Eastern Hawks | Western Bulldogs |
| 23 | 23 | Saturday August 21? | 1.00 pm? | Docklands | Western | Port Bay |
| 24 | Bye Round or The End | Saturday August 28 | 1.00 pm? | |||
| 25 | Finals 1 | Saturday September 3? | 1.00 pm? | 2021 | Finals | Series |
| 26 | Finals 2 | Saturday Sept 10? | 1.00 pm? | 2021 | Finals | Series |
| 27 | Preliminary Final | Saturday Sept 17? | 1.00 pm? | 2021 | Finals | Series |
| 28 | Grand Final | Saturday Sep 24 | 1.00 pm? | 2021 | Finals | Series |
Ladder
| Team | P | W | L | D | PF | PA | % | Pts |
| Central Demons | 22 | 17 | 4 | 1 | 1888 | 1443 | 130.8 | 70 |
| Port | 22 | 17 | 5 | - | 1884 | 1492 | 126.3 | 68 |
| Country Cats | 22 | 16 | 6 | - | 1845 | 1456 | 126.7 | 64 |
| Brisbane | 22 | 15 | 7 | - | 2131 | 1599 | 133.3 | 60 |
| Western | 22 | 15 | 7 | - | 1994 | 1501 | 132.8 | 60 |
| Sydney | 22 | 15 | 7 | - | 1986 | 1656 | 119.9 | 60 |
| Greater | 22 | 11 | 10 | 1 | 1768 | 1773 | 99.7 | 46 |
| Nth- West Bombers | 22 | 11 | 11 | - | 1416 | 1466 | 96.6 | 34 |
| West | 22 | 10 | 12 | - | 1752 | 1880 | 93.2 | 40 |
| Southern Saints | 22 | 10 | 12 | - | 1644 | 1796 | 91.5 | 40 |
| Fremantle | 22 | 10 | 12 | - | 1578 | 1825 | 86.5 | 40 |
| Eastern Tigers | 22 | 9 | 12 | 1 | 1743 | 1780 | 97.9 | 38 |
| Northern Blues | 22 | 8 | 14 | - | 1746 | 1972 | 88.5 | 32 |
| Eastern Hawks | 22 | 7 | 13 | 2 | 1629 | 1912 | 85.2 | 32 |
| Adelaide | 22 | 7 | 15 | - | 1616 | 1971 | 82.0 | 28 |
| Gold | 22 | 7 | 15 | - | 1430 | 1863 | 76.8 | 28 |
| Nth- East Magpies | 22 | 6 | 16 | - | 1557 | 1818 | 85.6 | 24 |
| Northern Kangaroos | 22 | 4 | 17 | 1 | 1458 | 2075 | 70.3 | 18 |
